Graphene patterned polyaniline-based biosensor for glucose detection

Tóm tắt

This paper describes a glucose electrochemical biosensor, layer-by-layer fabricated from graphene and polyaniline films. Graphene sheets (0.5 × 0.5 cm2 ) with the thickness of 5 nm (15 layers) were synthesized by thermal chemical vapor deposition (CVD) under ambient pressure on copper tapes. Then they were transferred into integrated Fe3O4-doped polyaniline (PANi) based microelectrodes. The properties of the nanocomposite films were thoroughly characterized by scanning electron microscopy (SEM), Raman spectroscopy, atomic force microscopy (AFM) and electrochemical methods, such as square wave voltametry (SWV) and chronoamperometry. The above graphene patterned sensor (denoted as Graphene/Fe3O4/PANi/GOx) shows much improved glucose sensitivity (as high as 47µA mM−1 cm−2 ) compared to a non-graphene one (10–30µA mM−1 cm−2 , as previously reported in the literature). It can be expected that this proof-of-concept biosensor could be extended for other highly sensitive biodetection.

Từ khoá

Keywords: graphene, glucose, electrochemical biosensor, layer-by-layer, polyaniline (PANi)

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