A novel nanofiber Cur-loaded polylactic acid constructed by electrospinning

Tóm tắt

Curcumin (Cur), extracted from the Curcuma longa L. plant, is well known for its anti-tumor, anti-oxidant, anti-inflammatory and anti-bacterial properties. Nanofiber mats of polylactic acid (PLA) loading Cur (5 wt%) were fabricated by electrospinning (e-spinning). Morphology and structure of the fibers were characterized by field emission scanning electron microscopy (FE-SEM) and Fourier transform infrared (FTIR) spectroscopy, respectively. The diameters of the obtained fibers varied from 200 to 300 nm. The release capacity of curcumin from curcumin-loaded PLA fibers was investigated in phosphate buffer saline (PBS) containing ethanol. After 24 h, 50% of the curcumin was released from curcumin-loaded PLA fibers. These results of electrospun (e-spun) fibers exhibit the potential for biomedical application.

Tài liệu tham khảo

[1] Bidone J, Melo A P P, Bazzo G C, Carmignan F, Soldi M S, Pires A T N and Lemos-Senna E 2009 Mater. Sci. Eng. C 29 588

[2] Cui W G, Zhou Y and Chang J 2010 Sci. Technol. Adv. Mater. 11 1

[3] Huang Z M, Zhang Y Z, Kotaki M and Ramakrishna S 2003 Compos. Sci. Technol. 63 2223

[4] Puppi D, Piras A M, Detta N, Dinucci D and Chiellini F 2010 Acta Biomater. 6 1258

[5] Sill T J and Von Recum H A 2008 Biomaterials 29 1989

[6] Suwantong O, Ruktanonchai U and Supaphol P 2008 Polymers 49 4239

[7] Xu X, Chen X, Ma P and Wang A 2008 Eur. J. Pharm. Biopharm. 70 165

[8] Yu D G, Zhang X F, Shen X X, Brandford-White C and Zhu L M 2009 Polym. Int. 58 1010

[9] Kontogiannopoulos K N, Assimopoulou A N, Tsivintzelis I, Panayiotou C and Papageorgiou V P 2011 Int. J. Pharm. 409 216
[10] Kenawy E R, Bowlin G L, Mansfield K, Layman J, Simpson D G and Sanders E H 2002 J. Control. Release 81 57

[11] Zong X H, Kim K, Fang D F, Ran S F, Hsiao B S and and Chu 2002 Polymers 43 4403

[12] Langer R and Vacanti J P 1993 Science 260 920

[13] Luu Y K, Kim K, Hsiao B S, Chu B and Hadjiargyrou M 2003 J. Control. Release 89 341

[14] Pan H, Jiang H L and Chen W L 2008 Biomaterials 29 1583

[15] Bini T B, Gao S J, Tan T C, Wang S, Lim A, Hai L B and Ramakrishna S 2004 Nanotechnology 15 1459

[16] Zhong X H, Bien H, Chung C Y, Yin L H, Fang D F, Hsiao B S, Chu B and Entcheva E 2005 Biomaterials 26 5330

[17] Sharma R A, Gescher A J and Steward W P 2005 Eur. J. Cancer 41 1955

[18] Jayaprakasha G K, Jagan L, Rao M and Sakariah K K 2005 Trends Food Sci. Technol. 15 533

[19] Jayaprakasha G K, Rao L J and Sakariah K K 2006 Food Chem. 98 720

[20] Maheshwari R K, Singh A K, Gaddipati J and Srimal R C 2006 Life Sci. 78 2081

[21] Arbiser J L, Klauber N, Rohan R, van Leeuwen R, Huang M T, Fisher C, Flynn E and Byers H R 1998 Mol. Med. 4 376

[22] Chen H W and Huang H C 1998 Br. J. Pharmacol. 124 1029

[23] Kumar, Dhawan S, Hardegen N J and Aggarwal B B 1998 Biochem. Pharmacol. 55 775

[24] Park J S 2010 Adv. Nat. Sci.: Nanosci. Nanotechnol. 1 043002

[25] Nguyen T T T, Tae B and Park J S 2011 J. Mater. Sci. 46 6528

[26] Yallapua M M, Jaggi M and Chauhana S C 2010 Colloid Surf. B 79 113

[27] Wang P, Hu W and Su W 2008 Anal. Chim. Acta 615 54

[28] Wang N, Zhang X, Ma X and Fang J 2008 Polym. Degrad. Stab. 93 1044

[29] Suwantong O, Opanasopit P, Ruktanonchai U and Supaphol P 2007 Polymers 48 7546

Các bài trích dẫn đến

1. Radhakrishnan Sridhar, Rajamani Lakshminarayanan, Kalaipriya Madhaiyan, Veluchamy Amutha Barathi, Keith Hsiu Chin Lim, Seeram Ramakrishna. Electrosprayed nanoparticles and electrospun nanofibers based on natural materials: applications in tissue regeneration, drug delivery and pharmaceuticals in Chemical Society Reviews (Vol. 44, No. 3, 2015)
2. Romi Sukmawan, Hitoshi Takagi, Antonio Norio Nakagaito. Strength evaluation of cross-ply green composite laminates reinforced by bamboo fiber in Composites Part B: Engineering (Vol. 84, 2016)
3. Adriana Blanco-Padilla, Amparo López-Rubio, Guadalupe Loarca-Pina, Laura G Gómez-Mascaraque, Sandra Mendoza. Characterization, release and antioxidant activity of curcumin-loaded amaranth-pullulan electrospun fibers in LWT-Food Science and Technology (Vol. 63, No. 2, 2015)
4. Ravi Babu Valapa, G Pugazhenthi, Vimal Katiyar. Fabrication and characterization of sucrose palmitate reinforced poly (lactic acid) bionanocomposite films in Journal of Applied Polymer Science (Vol. 132, No. 3, 2015)
5. Mona Fallah, S Hajir Bahrami, Marziyeh Ranjbar-Mohammadi. Fabrication and characterization of PCL/gelatin/curcumin nanofibers and their antibacterial properties in Journal of industrial textiles (Vol. 46, No. 2, 2016)
6. Nadeesh Madusanka, KM Nalin de Silva, Gehan Amaratunga. A curcumin activated carboxymethyl cellulose–montmorillonite clay nanocomposite having enhanced curcumin release in aqueous media in Carbohydrate polymers (Vol. 134, 2015)
7. Pradeep Kumar Singh, Kirtee Wani, Ruchika Kaul-Ghanekar, Asmita Prabhune, Satishchandra Ogale. From micron to nano-curcumin by sophorolipid co-processing: highly enhanced bioavailability, fluorescence, and anti-cancer efficacy in RSC Advances (Vol. 4, No. 104, 2014)
8. Zahra Rafiee, Mohammad Nejatian, Marjan Daeihamed, Seid Mahdi Jafari. Application of different nanocarriers for encapsulation of curcumin in Critical reviews in food science and nutrition (2018)
9. Shubham Jain, Sai Rama Krishna Meka, Kaushik Chatterjee. Curcumin eluting nanofibers augment osteogenesis toward phytochemical based bone tissue engineering in Biomedical Materials (Vol. 11, No. 5, 2016)
10. Charlotte Jacobsen, Pedro J García-Moreno, Ana C Mendes, Ramona V Mateiu, Ioannis S Chronakis. Use of electrohydrodynamic processing for encapsulation of sensitive bioactive compounds and applications in food in Annual review of food science and technology (Vol. 9, 2018)
11. Elhamalsadat Shekarforoush, Ana Mendes, Vanessa Baj, Sophie Beeren, Ioannis Chronakis. Electrospun phospholipid fibers as micro-encapsulation and antioxidant matrices in Molecules (Vol. 22, No. 10, 2017)
12. Gyuldzhan Yakub, Antoniya Toncheva, Nevena Manolova, Iliya Rashkov, Dobri Danchev, Veselin Kussovski. Electrospun polylactide‐based materials for curcumin release: Photostability, antimicrobial activity, and anticoagulant effect in Journal of Applied Polymer Science (Vol. 133, No. 5, 2016)
13. Wenqiang Liu, Yu Dong, Dongyan Liu, Yuxia Bai, Xiuzhen Lu. Polylactic acid (PLA)/cellulose nanowhiskers (CNWs) composite nanofibers: microstructural and properties analysis in Journal of Composites Science (Vol. 2, No. 1, 2018)
15. Faruq Mohammad, Tanvir Arfin, Hamad A Al-Lohedan. Biocompatible polylactic acid-reinforced nickel–arsenate composite: Studies of electrochemical conductivity, mechanical stability, and cell viability in Materials Science and Engineering: C (2019)
19. Leonardo Santana, Jorge Lino Alves, Sabino Netto, Aurélio da Costa, Claudia Merlini. A comparative study between PETG and PLA for 3D Printing through thermal, chemical and mechanical characterization in Matéria (Rio de Janeiro) (Vol. 23, No. 4, 2018)